Skip to Content

HCA Healthcare Research Institute

HCA Healthcare Research Institute is the multispecialty clinical research arm of HCA Healthcare. Our expert physicians work with trusted pharmaceutical and biotechnology partners to unlock insights from real-world data and conduct clinical studies leading to breakthroughs in science, medicine and care for all people.

Transforming patient care through clinical research

The Research Institute serves as a connector, bringing together trusted partners and community-based providers to support patient-centered clinical research.

As part of a learning health system, the Research Institute leverages our scale to bring advanced therapies and technologies to our patients in their local facilities. Research is at the core of how we deliver on our mission – Above all else, we are committed to the care and improvement of human life.

Dive deeper into stories from our clinical research See the latest from our network

Who we are

HCA Healthcare Research Institute is the multispecialty clinical research arm of HCA Healthcare committed to advancing care for every individual through our affiliated network of clinicians and sites.

How we do it

The Research Institute is a connector. We bring together trusted pharmaceutical and biotechnology partners with community-based clinicians to impact more people in more places.

What we offer 

We offer a single point of contact to streamline trials and the site activation process, accelerated start-up timelines to make feasibility, contract and budget negotiations more efficient, access to diverse and quality sites with proven performance, and experienced principal investigators across a network of multiple therapeutic areas.

  • 50

    Sites in the network and growing

  • 750+

    Industry-sponsored trials

  • 200

    National experienced principal investigators

  • 9

    Specialties

*Data as of July 23, 2025

Improving lives in more ways

“Research is vitally important to healthcare and American medicine; therefore, it is important to HCA Healthcare.”
Dr. Michael Cuffe
Executive Vice President, Chief Clinical Officer

Contact Us

Our network

HCA Healthcare Research Institute’s site network connects sponsors and contract research organizations with national scientific key opinion leaders and community-based hospitals across the country. We perform research in a variety of therapeutic areas, including oncology, cardiology, neuroscience, pulmonary and thoracic, and inpatient surgical/device trials, collaborating across physician groups to help improve patient access and maximize start-up efficiency.

Our patients

When you participate in a clinical research trial, you contribute to unlocking breakthroughs in science and the future of healthcare. Many medications and treatments would not exist without research participants. People of all ages and backgrounds can participate in clinical trials. Talk to your doctor to learn more about participating in a clinical trial and contributing to the future of medicine.

Our partners

HCA Healthcare is a leader in research. Our approximately 44 million annual patient encounters provide a wealth of data that is utilized for records-based initiatives.

The Research Institute serves as a valuable partner and liaison between research study sponsors and our network of sites in communities across the country.

The Research Institute offers:

  • A single point of contact to streamline trials and site activation
  • Multi-specialty centralized support services
  • Access to diverse, quality sites with proven performance
  • Experienced principal investigator support across a network of therapeutic areas

Our physicians

As part of a learning health system, we are unlocking insights into real-world data and clinical studies that lead to scientific breakthroughs and transform patient care.

Join a growing network of more than 200 principal investigators participating in local and national research initiatives, advancing care for our patients.

Advancing patient care to improve more lives

The HCA Healthcare Research Institute helps shape the future of patient care industrywide, bringing breakthroughs in science and medicine to our patients in their community.

The HCA Healthcare Research Institute helps shape the future of patient care industrywide, bringing breakthroughs in science and medicine to our patients in their community.

Learn More About Our Impact

Innovative care close to home

With 50 sites across eleven states, the Research Institute’s capacity and capabilities continue to strengthen across the enterprise. Our programs support nine specialties – Cardiac and Vascular, Oncology, Infectious Disease, Pulmonary and Thoracic, Women and Children’s, Neuroscience, Musculoskeletal, Robotics and Behavioral Health.

Capital

CJW Medical Center

  • Cardiac and Vascular, Oncology, Infectious Disease, Neuroscience

Henrico Doctor’s Hospital

  • Cardiac and Vascular, Oncology

Continental

HCA HealthONE Aurora

  • Cardiac and Vascular

HCA HealthONE Presbyterian St. Luke’s

  • Musculoskeletal

HCA HealthONE Rose

  • Musculoskeletal

HCA HealthONE Sky Ridge

  • Musculoskeletal

HCA HealthONE Swedish

  • Neuroscience, Musculoskeletal

East Florida

HCA Florida JFK Hospital

  • Cardiac and Vascular, Neuroscience, Oncology, Musculoskeletal

HCA Florida Mercy Hospital

  • Cardiac and Vascular, Oncology, Robotics

Far West

Los Robles Regional Medical Center

  • Cardiac and Vascular

MountainView Hospital

  • Robotics

Riverside Community Hospital

  • Cardiac and Vascular, Pulmonary and Thoracic, Neuroscience

Gulf Coast

Corpus Christi Medical Center

  • Cardiac and Vascular

HCA Houston Healthcare Clear Lake

  • Cardiac and Vascular

HCA Houston Healthcare Medical Center

  • Cardiac and Vascular

HCA Houston Healthcare Kingwood

  • Neuroscience

Rio Grande Regional Hospital

  • Cardiac and Vascular

The Woman’s Hospital of Texas

  • Women and Children's

MidAmerica

Centerpoint Medical Center

  • Oncology

Menorah Medical Center

  • Oncology

Research Medical Center

  • Oncology

Mountain

St. Mark’s Hospital

  • Cardiac and Vascular

North Carolina

Mission Hospital

  • Cardiac and Vascular, Oncology, Pulmonary and Thoracic, Neuroscience

North Florida

HCA Florida Ocala Hospital

  • Cardiac and Vascular, Neuroscience

North Texas

Medical City Arlington

  • Neuroscience

Medical City Dallas

  • Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic, Women and Children's, Musculoskeletal

Medical City Fort Worth

  • Cardiac and Vascular, Neuroscience

Medical City Green Oaks Hospital

  • Behavioral Health

Medical City Heart Hospital

  • Cardiac and Vascular, Infectious Disease, Musculoskeletal

Medical City Plano

  • Cardiac and Vascular, Neuroscience, Musculoskeletal, Infectious Disease

San Antonio

Methodist Hospital

  • Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic

Methodist Hospital Metropolitan

  • Cardiac and Vascular

Methodist Hospital Stone Oak

  • Cardiac and Vascular, Infectious Disease

Methodist Hospital Texsan

  • Cardiac and Vascular

South Atlantic

Grand Strand Medical Center

  • Cardiac and Vascular

Trident Medical Center

  • Cardiac and Vascular, Oncology

HCA Florida Memorial Hospital

  • Cardiac and Vascular, Pulmonary and Thoracic

TriStar

TriStar Centennial Medical Center

  • Cardiac and Vascular, Oncology, Infectious Disease, Pulmonary and Thoracic, Neuroscience

TriStar Skyline Medical Center

  • Neuroscience

West Florida

HCA Florida Brandon Hospital

  • Cardiac and Vascular, Infectious Disease, Women and Children’s, Neuroscience

HCA Florida West Tampa

  • Oncology

HCA Florida Fawcett Hospital

  • Cardiac and Vascular

HCA Florida Largo Hospital

  • Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic

HCA Florida Northside Hospital

  • Cardiac and Vascular, Infectious Disease

HCA Florida Trinity Hospital

  • Infectious Disease, Musculoskeletal, Robotics